Prevalence of Non-alcoholic Fatty liver Disease in patients of Diabetes Mellitus in Referred Clinic in Kosti Teaching Hospital

Abstract

Introduction:
Non-alcoholic fatty liver disease (NAFLD) is very common pathological conditions worldwide that is closely
associated with the clinical features of metabolic syndrome and is characterized by substantial inter patient
variability in severity and rate of liver disease progression.
Methods:
This is a prospective hospital based study which was performed in Kosti city-White Nile State (Sudan). The study
population comprised diabetic patients whom are randomly selected from Kosti Teaching Hospital. It was
conducted in the period between 1/2/2019 to 1/4/2019.The sample size was on an average of 150 cases, categorized
further into 80 cases and 70 controls. All cases were subjected to full history, proper examination, lab investigations
and abdominal ultrasound. Information were collected, classified into three forms of data and analyzed accordingly.
Results:
The overall prevalence of non alcoholic liver disease in diabetes mellitus is 68%. This prevalence increases with
age as there is remarkable increase in developing nonalcoholic liver disease mainly in patients of old ages. The
prevalence has gender variation as it reveals predominance of female in diabetes and diabetes with hypertension and
no gender variation in diabetes with coronary artery disease. Prevalence of non alcoholic liver disease increased in
urban areas in diabetes with coronary artery disease and increased in rural areas in diabetes and diabetes with
hypertensive patients. Prevalence of nonalcoholic liver disease increased with duration of diabetes mellitus.
Conclusion:
Based on the findings of the presents study, the prevalence of nonalcoholic fatty liver disease in diabetes mellitus is
related to age, sex, residence, duration of disease.